Varicose Vein Before and After Photos

Symptoms and appearance results

In 2 placebo-controlled studies, most patients treated with Varithena® (polidocanol injectable foam) experienced these results:
  • Improved symptoms
    The majority of patients reported improvement in symptoms including heaviness, achiness, swelling, throbbing, and itching (HASTI™ Symptoms).
  • Improved vein appearance
    The majority of patients experienced improved vein appearance in assessments by both patients and doctors.

Safety results

The most common side effects seen with Varithena were leg pain or discomfort, injection site bruising or pain, and potentially serious blood clots in the leg veins.
These are not all of the possible side effects of Varithena.
See Important Safety Information.

Before & After Photos

These photos show results after one treatment with Varithena. Additional treatment may be needed, depending on the number and size of veins to be treated. Your results may vary.

*VANISH-2 Study

Click here for
Case Studies showing treatment of GSV system veins using Varithena®


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit, or call 1-800-FDA-1088.

This website is intended for visitors from the United States.


Varithena® (polidocanol injectable foam) is a prescription medicine used to treat varicose veins caused by problems with the great saphenous vein (GSV) and other related veins in the leg's GSV system. Varithena® improves symptoms related to or caused by varicose veins, and the appearance of varicose veins.


You should not be treated with Varithena® if you are allergic to polidocanol or have clots in your blood vessels.

Severe allergic reactions have been reported in people treated with liquid forms of polidocanol and some patients have died from these reactions. Varithena® is a foam made from polidocanol. A healthcare professional will observe you for signs of allergic reactions for at least 10 minutes after you are treated with Varithena®.

Tell your doctor about all your medical conditions, including if you have:

  • Arterial disease (a disease of the blood vessels)
  • Reduced mobility
  • A history of blood clots in the veins or lungs
  • Had major surgery in the past 3 months
  • Recently had a long hospital stay
  • Become pregnant or were recently pregnant

The most common side effects seen with Varithena® are leg pain or discomfort, injection site bruising or pain, and potentially serious blood clots in the leg veins. These are not all the possible side effects of Varithena®. Tell your healthcare provider about any side effect that bothers you or that does not go away. You can also report side effects to the FDA at 1-800-FDA-1088. Varithena® is administered by your doctor. Doctors using Varithena® must be experienced in vein procedures and trained in using Varithena®.

See Full Prescribing Information for Varithena®.